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16005

Sigma-Aldrich

Paraformaldehyde

meets analytical specification of DAC, 95.0-100.5%

Synonym(s):

Polyoxymethylene

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About This Item

Linear Formula:
HO(CH2O)nH
CAS Number:
30525-89-4
Molecular Weight:
30.03 (as monomer)
MDL number:
MFCD00133991
UNSPSC Code:
12352100
PubChem Substance ID:
24849849
NACRES:
NA.22

vapor density

1.03 (vs air)

vapor pressure

<1.45 mmHg ( 25 °C)

Assay

95.0-100.5%

form

pellets

autoignition temp.

572 °F

quality

meets analytical specification of DAC

expl. lim.

73 %

technique(s)

NMR: suitable

impurities

residual solvents, in accordance
<0.1% sulfated ash
10 ppm heavy metals (as Pb)

mp

120-170 °C (lit.)

solubility

water: insoluble

density

0.88 g/mL at 25 °C (lit.)

suitability

in accordance for appearance of solution
suitable for acidity or alkalinity (complying)

storage temp.

2-8°C

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

Buffered picric acid-paraformaldehyde fixative is suitable for use in electron microscopy and light-microscopic immunocytochemistry.

Application

Paraformaldehyde was used in the preparation of azomethine ylide, required for the synthesis of amine-modifying single-walled carbon nanotubes. It was also used in the preparation of α-methylenechromanes, α-methylenequinoline and ortho-quinone methides.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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P Somogyi et al.
Neuroscience, 7(7), 1779-1783 (1982-07-01)
The buffered picric acid paraformaldehyde fixative originally recommended for electronmicroscopy and which has since been used occasionally for light-microscopic immunocytochemistry, has been supplemented with glutaraldehyde and used as primary fixative for the perfusion of rat brains. In the basal ganglia
J Justin Mulvey et al.
International journal of nanomedicine, 9, 4245-4255 (2014-09-18)
We aimed to create a more robust and more accessible standard for amine-modifying single-walled carbon nanotubes (SWCNTs). A 1,3-cycloaddition was developed using an azomethine ylide, generated by reacting paraformaldehyde and a side-chain-Boc (tert-Butyloxycarbonyl)-protected, lysine-derived alpha-amino acid, H-Lys(Boc)-OH, with purified SWCNT
José C J M D S Menezes et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 20(42), 13644-13655 (2014-08-30)
In view of increasing demands for efficient photosensitizers for photodynamic therapy (PDT), we herein report the synthesis and photophysical characterizations of new chlorin e6 trimethyl ester and protoporphyrin IX dimethyl ester dyads as free bases and Zn(II) complexes. The synthesis of these
Lingling Chen et al.
Scientific reports, 7(1), 12218-12218 (2017-09-25)
Optical clearing methods can facilitate deep optical imaging in biological tissue by reducing light scattering and this has enabled accurate three-dimensional signal visualization and quantification of complex biological structures. Unfortunately, existing optical clearing approaches present a compromise between maximizing clearing
Ting Yao et al.
FEBS open bio, 6(7), 707-719 (2016-07-12)
Decorin (DCN) is a major member of the small leucine-rich proteoglycan (SLRP) family that is critically involved in tumorigenesis and the development of metastasis of cancers, including glioma. Overexpression of DCN was indicated to suppress glioma cell growth. However, the
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