15399
Boc-Lys(2-Cl-Z)-OH
≥98.0% (T)
Synonym(s):
Nα-Boc-Nε-(2-chloro-Z)-L-lysine
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About This Item
Empirical Formula (Hill Notation):
C19H27ClN2O6
CAS Number:
Molecular Weight:
414.88
Beilstein:
3598068
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥98.0% (T)
optical activity
[α]20/D −11±1°, c = 2% in DMF
mp
70-73 °C
storage temp.
2-8°C
SMILES string
CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1Cl)C(O)=O
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Application
Protected lysine especially suited for solid phase peptide synthesis; the 2-CI-Z protection is about 50 times more stable than the Z-group.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N -branching at lysine during solid-phase peptide synthesis.
B W Erickson et al.
Journal of the American Chemical Society, 95(11), 3757-3763 (1973-05-30)
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