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11318

Sigma-Aldrich

5-Amino-1-pentanol solution

50% in H2O

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About This Item

Linear Formula:
NH2(CH2)5OH
CAS Number:
Molecular Weight:
103.16
Beilstein:
1732302
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Pricing and availability is not currently available.

concentration

50% in H2O

bp

122 °C/16 mmHg (lit.)

density

0.99 g/mL at 20 °C

SMILES string

NCCCCCO

InChI

1S/C5H13NO/c6-4-2-1-3-5-7/h7H,1-6H2

InChI key

LQGKDMHENBFVRC-UHFFFAOYSA-N

General description

5-Aminopentan-1-ol is a colorless to faint yellow liquid.

Application

5-amino-1-pentanol is used in the preparation of fibres from random copolypeptides consisting of N-hydroxyalkyl L-glutamine and gamma-methyl L-glutamate with different monomer ratios[1]. 5-amino-1-pentanol (5-Aminopentan-1-ol) was also used in the preparation of 5-phthalimidopentanal[2] and tetracyclic core of the natural compound (+/-)-dibromoagelaspongin[3].

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1A

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T Hayashi et al.
Biomaterials, 11(6), 409-413 (1990-08-01)
Fibres from random copolypeptides consisting of N-hydroxyalkyl L-glutamine and gamma-methyl L-glutamate with different monomer ratios were prepared by aminoalcoholysis of a poly(gamma-methyl L-glutamate) fibre with 2-amino-1-ethanol or 5-amino-1-pentanol, both with 1,8-octamethylenediamine as cross-linking agent. The initial tensile properties as well
Miller D, et al.
Journal of the Chemical Society. Perkin Transactions 1, 1, 131-142 (1998)
Sylvain Picon et al.
Organic letters, 11(12), 2523-2526 (2009-05-19)
A six-step synthesis of the tetracyclic core of the natural compound (+/-)-dibromoagelaspongin, isolated from Agelas sp. Sponge, was achieved from the commercially available 5-aminopentan-1-ol, 2-trichloroacetylpyrrole, and 2-aminopyrimidine. Following a biomimetic inspired approach, successive oxidative reactions including the final DMDO biomimetic
Ahmed A Eltoukhy et al.
ACS nano, 8(8), 7905-7913 (2014-07-11)
Despite intensive research effort, the rational design of improved nanoparticulate drug carriers remains challenging, in part due to a limited understanding of the determinants of nanoparticle entry and transport in target cells. Recent studies have shown that Niemann-Pick C1 (NPC1)
Antonella Mangraviti et al.
ACS nano, 9(2), 1236-1249 (2015-02-03)
Biodegradable polymeric nanoparticles have the potential to be safer alternatives to viruses for gene delivery; however, their use has been limited by poor efficacy in vivo. In this work, we synthesize and characterize polymeric gene delivery nanoparticles and evaluate their

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