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Sigma-Aldrich

L-Arginine methyl ester dihydrochloride

≥98.0% (AT)

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About This Item

Linear Formula:
HN=C(NH2)NH(CH2)3CH(NH2)COOCH3 · 2HCl
CAS Number:
26340-89-6
Molecular Weight:
261.15
Beilstein:
4159929
EC Number:
247-622-0
MDL number:
MFCD00038948
UNSPSC Code:
12352209
PubChem Substance ID:
57646878
NACRES:
NA.22

Assay

≥98.0% (AT)

form

powder

optical activity

[α]20/D +21±1°, c = 2.5% in methanol

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

~190 °C (dec.)

application(s)

peptide synthesis

SMILES string

Cl.Cl.COC(=O)[C@@H](N)CCCNC(N)=N

InChI

1S/C7H16N4O2.2ClH/c1-13-6(12)5(8)3-2-4-11-7(9)10;;/h5H,2-4,8H2,1H3,(H4,9,10,11);2*1H/t5-;;/m0../s1

InChI key

XQYZOBNLCUAXLF-XRIGFGBMSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Olga Lekontseva et al.
The Journal of pharmacology and experimental therapeutics, 339(2), 367-375 (2011-08-03)
Estrogen has antihypertensive and vasorelaxing properties, partly via activation of endothelial nitric-oxide synthase (eNOS). Recently, neuronal nitric-oxide synthase (nNOS) has been detected in vascular cells, although the significance of this is unclear. Estrogen was found to stimulate nNOS in certain
Matthew F Bush et al.
Journal of the American Chemical Society, 129(6), 1612-1622 (2007-01-26)
The gas-phase structures of protonated and alkali metal cationized arginine (Arg) and arginine methyl ester (ArgOMe) are investigated with infrared spectroscopy and ab initio calculations. Infrared spectra, measured in the hydrogen-stretch region, provide compelling evidence that arginine changes from its
Uta Hillebrand et al.
Journal of hypertension, 27(3), 517-526 (2009-03-31)
Nebivolol (NEB) is a [beta]1-receptor blocker with nitric oxide-dependent vasodilating properties. NEB-induced nitric oxide release is mediated through the estrogen receptor. Here, we tested the hypothesis that NEB decreases endothelial cell stiffness and that these effects can be abolished by
Matthew W Forbes et al.
The journal of physical chemistry. A, 111(46), 11759-11770 (2007-11-02)
The structures of cationized arginine complexes [Arg + M]+, (M = H, Li, Na, K, Rb, Cs, and Ag) and protonated arginine methyl ester [ArgOMe + H]+ have been investigated in the gas phase using calculations and infrared multiple-photon dissociation
Alessandro Rubini
Respiration; international review of thoracic diseases, 82(5), 468-475 (2011-08-09)
Data describing the inhibitory effects of nitric oxide synthase (NOS) on respiratory mechanics are conflicting, and no data are available concerning possible effects on the viscoelasticity of the respiratory system, on the inspiratory work of breathing (WOB) or on respiratory
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