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Merck

MMP3

matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Synonyms:
CHDS6, MMP-3, SL-1, STMY, STMY1, STR1
Species:
UniProtKB ID:
Gene ID:
  • Human(4314) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17392) matrix metallopeptidase 3
  • Rat(171045) matrix metallopeptidase 3
  • Domestic Rabbit(100009111) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • naked mole-rat(101716622) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • domestic guinea pig(100729101) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • dog(403445) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • Horse(100034195) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • domestic cat(101081492) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • domestic cat(493666) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • sheep(101118895) matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • cow(281309) matrix metallopeptidase 3 (stromelysin 1, progelatinase)

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ELISA

Product Number
Description
Species
Human MMP-3 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
Mouse MMP-3 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MMP-3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-MMP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MMP3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human, mouse
Application
immunohistochemistry
western blot
Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4, clone 55-2A4, Chemicon®, from mouse,
Species Reactivity
human, pig, rat, sheep
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-MMP3 antibody produced in mouse, clone 4C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

Small Molecule - Inhibitor

Product Number
Description
Species
4-Phenylpyridine, 97%,
Species
human
Acetohydroxamic acid, 98%,
Species
human
4′-Hydroxy-4-biphenylcarbonitrile, 97%,
Species
human
4,4′-Dihydroxybiphenyl, 97%,
Species
human
α-Sexithiophene, ,
Species
human, rat

Proteins

Product Number
Description
Species
MMP-3 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MMP3,
Species
human
MISSION® esiRNA, targeting mouse Mmp3,
Species
mouse