T6830

Thyroglobulin human

• Synonym(s): Thyroglobulin human
• CAS Number: 9010-34-8
• UNSPSC Code: 12352202
• EC Number: 232-721-3
• NACRES: NA.56
• MDL number: MFCD01324794
• Form: lyophilized solid
• Assay: ≥95% (SDS-PAGE)
• Biological source: human

Properties

• biological source: human
• Quality Segment: 200
• assay: ≥95% (SDS-PAGE)
• form: lyophilized solid
• technique(s): cell culture | mammalian: suitable
• UniProt accession no.: P01266
• storage temp.: 2-8°C
• Gene Information: human ... TG(7038)

Description

General description

Human Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Human Thyroglobin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyryonine. Patients with Hashimoto′s thyroiditis or Graves′ disease, frequently develop antibodies against human Thyroglobulin. Thryoglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer and in Graves′ disease.

Biochem/physiol Actions

Thyroglobulin has been shown to induce expression of platelet activating factor in human peripheral blood mononuclear cells which is found elevated in some patients with thyroid disease.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable