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Key Documents

P8638

Sigma-Aldrich

Poly-DL-ornithine hydrobromide

suitable for cell culture, Mol wt 3,000-15,000

Synonym(s):

DL-Ornithine homopolymer hydrobromide

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Poly-DL-ornithine hydrobromide, mol wt 3,000-15,000

form

powder or solid

mol wt

3,000-15,000

technique(s)

cell culture | mammalian: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

Br.NCCCC(N)C(O)=O

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Application

Poly-DL-ornithine hydrobromide has been used to coat coverslips to seed dorsal root ganglion neurons from rats. It has also been used to coat dishes for mouse cortical neuron culture.

Biochem/physiol Actions

Poly-DL-ornithine is a basic polypeptide that provides an ideal condition for the growth of neurons in culture. It inhibits the growth of bacteria.

Analysis Note

Molecular weight based on viscosity. Also assayed by MALLS.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S H Parson et al.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 4(1), 99-106 (1995-03-01)
We have measured the effects of cytosine-beta-D-arabinofuranoside (AraC) on cell survival and neurite outgrowth in cultures of dissociated 4-6 day embryonic chick neural tube cells. High concentrations of AraC (greater than 100 microM) reduced neuronal cell survival and neurite outgrowth
Neuronal migration on laminin in vitro.
Liang S, Crutcher KA.
Brain Research. Brain Research Reviews, 66, 127-132 (1992)
Angela R Dixon et al.
Neuroscience letters, 703, 58-67 (2019-03-20)
Burgeoning use of segregated microfluidic platforms that parse somas and neurites into discrete compartments is fueling unique examinations of neuronal structure and physiology in a manner impossible to achieve with non-compartmentalized systems. However, even though this line of axon-soma polarizing
Serine residues at positions 162 and 166 of the rabies virus
phosphoprotein are critical for the induction of oxidative stress
in rabies virus infection
Wafa Kammouni
Journal of Neurovirology (2017)
Quantitative profiling of peptides from RNAs classified as noncoding
Sudhakaran Prabhakaran
Nature Communications (2014)

Articles

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