01897

Adenosine 5′-diphosphate disodium salt

≥90%

• Synonym(s): ADPdisodium salt, Disodium 5′-ADP, Disodium adenosine 5′-diphosphate, 5′-ADP-Na₂
• Empirical Formula (Hill Notation): C₁₀H₁₃N₅Na₂O₁₀P₂
• CAS Number: 16178-48-6
• Molecular Weight: 471.16
• PubChem Substance ID: 329747370
• eCl@ss: 32160414
• UNSPSC Code: 41106305
• NACRES: NA.51
• EC Number: 240-314-7
• MDL number: MFCD00066635
• Beilstein/REAXYS Number: 7563620
• Assay: ≥90%
• Form: powder or crystals
• Storage temp.: −20°C

Properties

• Quality Level: 100
• assay: ≥90%
• form: powder or crystals
• optical activity: [α]20/D −29.6±1°, c = 0.5% in 0.5 M Na₂HPO₄
• impurities: ≤10% water
• storage temp.: −20°C
• InChI: 1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChI key: ORKSTPSQHZNDSC-IDIVVRGQSA-L

Description

Application

Adenosine 5′-diphosphate disodium salt has been used as a purinergic G protein-coupled receptor P2Y12 agonistin platelet activation tests in blood samples.

Biochem/physiol Actions

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y₁ and P2Y₁₂. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)