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230553

Sigma-Aldrich

Sodium ethoxide solution

21 wt. % in ethanol

Synonym(s):

Sodium ethylate

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About This Item

Linear Formula:
CH3CH2ONa
CAS Number:
Molecular Weight:
68.05
Beilstein:
3593646
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

form

liquid

Quality Level

concentration

21 wt. % in ethanol

refractive index

n20/D 1.385

density

0.868 g/mL at 25 °C

SMILES string

[Na+].CC[O-]

InChI

1S/C2H5O.Na/c1-2-3;/h2H2,1H3;/q-1;+1

InChI key

QDRKDTQENPPHOJ-UHFFFAOYSA-N

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General description

Sodium ethoxide is an alkoxide salt mainly used as a strong base in organic reactions such as deprotonation, dehydration and dehalogenation.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 2 - Self-heat. 1 - Skin Corr. 1A - STOT SE 2

Target Organs

Eyes,Central nervous system

Supplementary Hazards

Storage Class Code

4.2 - Pyrophoric and self-heating hazardous materials

WGK

WGK 1

Flash Point(F)

48.2 °F - closed cup

Flash Point(C)

9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Sodium Ethoxide
Whitaker KS and Whitaker DT
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2001)
E D Clarkson et al.
Clinical chemistry, 44(2), 287-292 (1998-02-25)
A sensitive method is described to detect isolysergic acid diethylamide (iso-LSD) in urine. The compound was extracted from urine and converted to a C-8 carbanion by sodium ethoxide in ethanol. Protonation of the carbanion by water selectively produced LSD. The
S H Brorson et al.
Micron (Oxford, England : 1993), 26(4), 301-310 (1995-01-01)
The purpose of this investigation was to explain why deplasticizing of epoxy sections gives higher immunogold labeling than non-deplasticizing. The methods used were the following: (1) Comparison of the ratio of immunogold labeling of deplasticized and non-deplasticized sections with gold
Nicolas Masurier et al.
Carbohydrate research, 341(7), 935-940 (2006-03-15)
A comparative study of reaction conditions was performed for the synthesis of a 2-O-monobenzyl ether of cyclomaltoheptaose (beta-CD). Optimal conditions involved sodium ethoxide in Me(2)SO and benzyl bromide. The methodology was extended to the preparation of various 2(I)-O-iodobenzyl and 2(I)-O-carboxymethylbenzyl
E S H El Ashry et al.
Nucleosides, nucleotides & nucleic acids, 26(5), 437-451 (2007-06-21)
Regioselective alkylation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole (1) with hydroxy alkylating agents 2, 3, 13, and the 2,3-O-isopropylidene-1-O-(p-tolylsulfonyl)-glycerol (10) afforded the corresponding S-alkylated derivatives 6, 7, 11, and 14 under both conventional and microwave irradiation conditions; bentonite as a solid support gave better

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