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Key Documents

M84607

Sigma-Aldrich

N-Methylthiourea

97%

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About This Item

Linear Formula:
NH2CSNHCH3
CAS Number:
Molecular Weight:
90.15
Beilstein:
506162
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

form

crystals

mp

118-121 °C (lit.)

SMILES string

CNC(N)=S

InChI

1S/C2H6N2S/c1-4-2(3)5/h1H3,(H3,3,4,5)

InChI key

KQJQICVXLJTWQD-UHFFFAOYSA-N

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Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Chronic 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T S Plantinga et al.
Clinical pharmacology and therapeutics, 102(6), 1017-1024 (2017-05-10)
Agranulocytosis is a rare and serious adverse effect of antithyroid drugs, with unknown etiology. The present study aimed to uncover genetic susceptibility and underlying mechanisms of antithyroid drug-induced agranulocytosis (ATDAC). We studied two independent families with familial Graves' disease, of
Shruti Sharma et al.
International journal of molecular sciences, 14(1), 255-272 (2013-01-25)
Congenital heart defects with increased pulmonary blood flow (PBF) result in pulmonary endothelial dysfunction that is dependent, at least in part, on decreases in nitric oxide (NO) signaling. Utilizing a lamb model with left-to-right shunting of blood and increased PBF
D Debruyne et al.
Journal of pharmaceutical sciences, 74(2), 224-226 (1985-02-01)
A high-performance liquid chromatographic method is described which determines noxytiolin and 1-methyl-2-thiourea concentrations in serum. Valid determination requires immediate ultracentrifugation of blood samples, rapid serum freezing, and injection into the chromatograph within 6 h. A number of pharmacokinetic parameters were
Eiko Satoh et al.
Biological & pharmaceutical bulletin, 30(8), 1390-1394 (2007-08-02)
Previously, we have reported that the exposure of PC12 cells to the aluminum-maltolate complex (Al(maltol)(3)) results in decreased cell viability via the apoptotic cell death pathway. In this study, we have used several nitric oxide synthase (NOS) inhibitors and the
D F McCafferty et al.
Journal of clinical and hospital pharmacy, 9(3), 241-247 (1984-09-01)
The stability of two different concentrations (1% and 2.5% w/v) of noxythiolin (Noxyflex and Noxyflex S) stored at a variety of temperatures (4, 20 and 37 degrees C) in both plastic and glass bottles has been examined over a period

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