292206
2-Methyl-1,3-dioxolane
97%
Synonym(s):
Acetaldehyde ethylene acetal
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About This Item
Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
Molecular Weight:
88.11
Beilstein:
102520
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
97%
refractive index
n20/D 1.398 (lit.)
bp
82-83 °C (lit.)
density
0.982 g/mL at 25 °C (lit.)
functional group
ether
SMILES string
CC1OCCO1
InChI
1S/C4H8O2/c1-4-5-2-3-6-4/h4H,2-3H2,1H3
InChI key
HTWIZMNMTWYQRN-UHFFFAOYSA-N
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General description
The kinetics and mechanism of the gas-phase thermal decomposition of 2-methyl-1,3-dioxolane has been studied in a static system. The infrared spectra of solid, liquid and gaseous 2-methyl-1,3-dioxolane has been studied. Low-temperature ozonation of 2-methyl-1,3-dioxolane in acetone-d6, methyl acetate and tert-butyl methyl ether has been reported.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
28.4 °F - closed cup
Flash Point(C)
-2 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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H Tecle et al.
Life sciences, 52(5-6), 505-511 (1993-01-01)
The synthesis of a series of potent and efficacious 1-azabicyclo[2.2.1]heptan-3-one oxime muscarinic agonists is described. The oximes have extended appendages designed to span the cavity defined by the seven transmembrane helices of the muscarinic receptor. Some members of the series
T W Vickroy et al.
Federation proceedings, 43(13), 2785-2790 (1984-10-01)
The binding of agonists to muscarinic cholinergic receptors is well described by a binding model of multiple affinity states (superhigh, high, and low) in most central and peripheral tissues. Although previous studies of the influences by divalent cations, guanine nucleotides
T R Ward et al.
Brain research bulletin, 39(1), 49-55 (1996-01-01)
Recent reports indicate that organophosphate insecticides, in addition to inhibiting acetylcholinesterase activity, can bind directly at a subset of muscarinic receptors, which also bind cis-methyldioxolane with high affinity. Muscarinic receptors are known to act through at least two second messenger
T Nukada et al.
Molecular pharmacology, 24(3), 374-379 (1983-11-01)
Heat treatment of membranes from porcine caudate nucleus (50 degrees for 7 min) caused a marked decrease in [3H]cis-methyldioxolane [( 3H]CD) binding without affecting seriously the binding of [3H]3-quinuclidinyl benzilate [( 3H]QNB). Approximately 20% of the [3H]CD binding at 5
H B Wei et al.
European journal of pharmacology, 268(3), 381-391 (1994-08-16)
Murine fibroblast cell lines stably transfected with the rat muscarinic m1 or m2 receptor genes were used to study the homologous regulation of the muscarinic M1 or M2 receptors. The cells were pretreated with the muscarinic receptor agonists, (+)-cismethyl-dioxolane, carbachol
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