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1347609

USP

Irinotecan hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Irinotecan monohydrochloride trihydrate, [1,4′-Bipiperidine]-1′-carboxylic acid (S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester monohydrochloride trihydrate

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About This Item

Empirical Formula (Hill Notation):
C33H38N4O6 · HCl · 3H2O
CAS Number:
Molecular Weight:
677.18
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

agency

USP

API family

irinotecan

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Cl-].N21Cc3c(nc5c(c3CC)cc(cc5)OC(=O)N6CCC(CC6)N7CCCCC7)C2=CC4=C(COC(=O)[C@]4(O)CC)C1=O.O.O.O.[H+]

InChI

1S/C33H38N4O6.ClH.3H2O/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;;;;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H;3*1H2/t33-;;;;/m0..../s1

InChI key

KLEAIHJJLUAXIQ-JDRGBKBRSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Irinotecan hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Irinotecan Hydrochloride Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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This Item
PHR2717I14061347642
grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

pharmaceutical primary standard

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

USP

format

neat

format

-

format

-

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical small molecule

application(s)

-

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

API family

irinotecan

API family

irinotecan

API family

-

API family

irinotecan


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pictograms

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signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

  1. 안녕하세요. 해당 제품에서 DMSO 용매에 대한 용해도가 50mg/mL이 맞나요 ?

    1 answer
    1. This item is a product of the United States Pharmacopiea. The solubility is not determined on this hydrated form of Irinotecan HCl. However, the non-hydrated version, product I1406, Irinotecan HCl, is tested for solubility at 50 mg/mL in DMSO. Similar rates are expected for this material.

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