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Clozapine

Name: Clozapine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₁₉ClN₄

CAS Number:

5786-21-0

Molecular Weight:

326.82

NACRES:

NA.24

PubChem Substance ID:

329749443

UNSPSC Code:

41116107

MDL number:

MFCD00153785

eCl@ss:

25140904

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Properties

grade

pharmaceutical primary standard

agency

USP

API family

clozapine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)
pharmaceutical

format

neat

SMILES string

CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24

InChI

1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3

InChI key

QZUDBNBUXVUHMW-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), HTR2A(3356)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clozapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Clozapine Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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This Item	C2460000	C6305	1142108
USP 1142107 Clozapine	C2460000 Clozapine	Sigma-Aldrich C6305 Clozapine	USP 1142108 Clozapine Resolution Mixture
description United States Pharmacopeia (USP) Reference Standard	description European Pharmacopoeia (EP) Reference Standard	description -	description United States Pharmacopeia (USP) Reference Standard
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename -	manufacturer/tradename USP
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade -	grade pharmaceutical primary standard
application(s) pharmaceutical (small molecule) pharmaceutical	application(s) pharmaceutical (small molecule) pharmaceutical	application(s) -	application(s) pharmaceutical pharmaceutical (small molecule)
format neat	format neat	format -	format neat
agency USP	agency -	agency -	agency USP
Gene Information human ... DRD2(1813), HTR2A(3356)	Gene Information human ... DRD2(1813), HTR2A(3356)	Gene Information human ... ADRA1A(148), ADRA2A(150), ADRA2C(152), CHRM1(1128), DRD2(1813), DRD3(1814), DRD4(1815), HRH1(3269), HRH4(59340), HTR2A(3356), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR6(3362), HTR7(3363), KCNH1(3756), KCNH2(3757), UGT1A4(54657) rat ... Adra1a(29412), Adra2a(25083), Adrb1(24925), Chrm1(25229), Drd1a(24316), Drd2(24318), Drd3(29238), Drd4(25432), Hrh1(24448), Htr1a(24473), Htr1b(25075), Htr2a(29595), Htr2b(29581), Htr2c(25187), Htr3a(79246), Htr7(65032), Slc6a4(25553)	Gene Information human ... DRD2(1813), HTR2A(3356)

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Pictograms

GHS06

Signal Word

Danger

Hazard Codes

H301

Precautionary Statements

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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