T1330

Tamsulosin hydrochloride

≥98% (HPLC)

• Synonym(s): 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride
• Empirical Formula (Hill Notation): C₂₀H₂₈N₂O₅S · HCl
• CAS Number: 106463-17-6
• Molecular Weight: 444.97
• NACRES: NA.77
• PubChem Substance ID: 329826665
• UNSPSC Code: 12352200
• MDL number: MFCD00922997
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white
• solubility: DMSO: >10 mg/mL
• originator: Boehringer Ingelheim
• storage temp.: room temp
• SMILES string: Cl.CCOc1ccccc1OCCN[C@H](C)Cc2ccc(OC)c(c2)S(N)(=O)=O
• InChI: 1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1
• InChI key: ZZIZZTHXZRDOFM-XFULWGLBSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

Biochem/physiol Actions

Tamsulosin is a α1A/1D-adrenoceptor antagonist; Used as a treatment of BPH (benign prostatic hypertrophy).

Tamsulosin is an α1A/1D-adrenoceptor antagonist used as a treatment of benign prostatic hypertrophy (BPH). Its activity as an ? blocker also affects the iris, and has led to complications during cataract surgery, a condition called "floppy iris" syndrome.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable