SML2293

NSC61610

≥98% (HPLC)

• Synonym(s): CID247228, N1,N4-Bis[3-(1H-benzimidazol-2-yl)phenyl]-1,4-benzenedicarboxamide, NCI 61610
• Empirical Formula (Hill Notation): C₃₄H₂₄N₆O₂
• CAS Number: 500538-94-3
• Molecular Weight: 548.59
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: off-white to purple
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(C1=CC=C(C=C1)C(NC2=CC=CC(C3=NC4=C(N3)C=CC=C4)=C2)=O)NC5=CC(C6=NC7=C(N6)C=CC=C7)=CC=C5
• InChI: 1S/C34H24N6O2/c41-33(35-25-9-5-7-23(19-25)31-37-27-11-1-2-12-28(27)38-31)21-15-17-22(18-16-21)34(42)36-26-10-6-8-24(20-26)32-39-29-13-3-4-14-30(29)40-32/h1-20H,(H,35,41)(H,36,42)(H,37,38)(H,39,40)
• InChI key: WSXIJTIFOWCMIQ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

NSC61610 is an orally available and potent lanthionine synthetase C-like 2 (LANCL2) ligand that induces IL-10-mediated anti-inflammatory responses that ameliorate disease activity and decrease inflammatory lesions in the gut. Also NSC61610 modulates immune response to influenza A H1N1pdm virus infection in mice.

orally available and potent lanthionine synthetase C-like 2 (LANCL2) ligand

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable