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Merck

SML0180

Aceclidine hydrochloride

≥98% (HPLC)

Synonym(s):

1-Azabicyclo[2.2.2]oct-3-yl acetate hydrochloride, 3-Acetoxyquinuclidine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H15NO2 · HCl
CAS Number:
Molecular Weight:
205.68
PubChem Substance ID:
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
228-071-5
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to tan

solubility

H2O: ≥15 mg/mL at ~60 °C

storage temp.

−20°C

SMILES string

Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2

InChI

1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1

InChI key

LWWSARSTZGNKGV-FVGYRXGTSA-N

Application

Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.

Biochem/physiol Actions

Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.
Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.
Muscarinic receptor partial agonist
Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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