SML0129

AC-265347

≥98% (HPLC)

• Synonym(s): 1-(1,3-benzothiazol-2-yl)-1-(2,4-dimethylphenyl)ethanol, a-(2,4-Dimethylphenyl)-a-methyl-2-benzothiazolemethanol.
• Empirical Formula (Hill Notation): C₁₇H₁₇NOS
• CAS Number: 1253901-26-6
• Molecular Weight: 283.39
• NACRES: NA.77
• PubChem Substance ID: 329825179
• UNSPSC Code: 12352200
• MDL number: MFCD20527324
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥19 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cc1ccc(c(C)c1)C(C)(O)c2nc3ccccc3s2
• InChI: 1S/C17H17NOS/c1-11-8-9-13(12(2)10-11)17(3,19)16-18-14-6-4-5-7-15(14)20-16/h4-10,19H,1-3H3
• InChI key: IGSZVEPQZANNAB-UHFFFAOYSA-N

Description

Application

AC-265347 may be used in calcium-sensing receptor-mediated signaling.

Biochem/physiol Actions

AC-265347 is a calcimimetic that acts as agonist to calcium-sensing receptor. It reduces serum parathyroid hormone and plasma ionizable calcium.

AC-265347 is a human calcium-sensing receptor (CaSR) allosteric agonist. AC-265347 activates CaSR signaling in cellular proliferation and phosphatidyl inositol (PI) hydrolysis assays.

AC-265347 is a human calcium-sensing receptor (CaSR) allosteric agonist; calcimimetic

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable