SCP0085

Caspase 3 Substrate (PKC)

≥95% (HPLC), lyophilized

• Empirical Formula (Hill Notation): C₂₆H₃₅N₇O₁₂S₁
• Molecular Weight: 669.66
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• Product Name: Caspase 3 Substrate (PKC), chromogenic,
• assay: ≥95% (HPLC)
• form: lyophilized
• composition: Peptide Content, ≥70%
• storage condition: protect from light
• storage temp.: −20°C

Description

Application

Caspase 3, a cysteine protease activator of caspase 6 and caspase 7, metabolizes amyloid-β 4A precursor protein. Caspase 3 may be detected using a variety of chromogenic and fluorogenic peptide substrates built around the DxxD (asp-x-x-asp) sequences DMQD and DEVD such as Ac-DMQD-pNa (Acetyl-Asp-Met-Gln-Asp-p- nitroanalide), chromogenic; Ac-DMQD-AMC (Acetyl-Asp-Met-Gln-Asp- amino-4-methylcoumarin), fluorogenic and Ac-DEVD-4M2Na.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable