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P4510

Poly-ε-Cbz-L-lysine

mol wt 500-4,000

Synonym(s):

N6-[(phenylmethoxy)carbonyl]-L-lysine homopolymer

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About This Item

CAS Number:
UNSPSC Code:
12352209
NACRES:
NA.26
MDL number:
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form

powder

Quality Segment

mol wt

500-4,000

color

white

storage temp.

−20°C

SMILES string

[N+H3][C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)[O-]

InChI

1S/C14H20N2O4/c15-12(13(17)18)8-4-5-9-16-14(19)20-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,15H2,(H,16,19)(H,17,18)/t12-/m0/s1

InChI key

CKGCFBNYQJDIGS-LBPRGKRZSA-N

Application


  • Transfection by polyethyleneimine-coated microspheres.: This study explores the use of Poly-e-Cbz-L-lysine in coating microspheres with polyethyleneimine for enhanced cell transfection, demonstrating improved efficiency and potential applications in gene therapy (Manuel WS et al., 2001).

  • Transfection of cells mediated by biodegradable polymer materials with surface-bound polyethyleneimine.: The research focuses on biodegradable polymer materials, including Poly-e-Cbz-L-lysine, for cell transfection, highlighting their biodegradability and effectiveness in delivering genetic material (Zheng J et al., 2000).

  • Production of microspheres with surface amino groups from blends of Poly(Lactide-co-glycolide) and Poly(epsilon-CBZ-L-lysine) and use for encapsulation.: This paper discusses the creation of microspheres with surface amino groups using blends of Poly-e-Cbz-L-lysine, which are then used for encapsulating active agents, indicating applications in drug delivery systems (Zheng J et al., 1999).

  • Modification of materials formed from poly(L-lactic acid) to enable covalent binding of biopolymers: application to high-density three-dimensional cell culture in foams with attached collagen.: The study examines the modification of poly(L-lactic acid) materials with Poly-e-Cbz-L-lysine to covalently bind biopolymers, facilitating high-density 3D cell culture applications (Zheng J et al., 1998).

Analysis Note

Molecular weight by Electrospray Mass-Spectrometry

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

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This Item
P7890A4021C3637
form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

color

white

color

white to off-white

color

colorless to white

color

white to off-white

mol wt

500-4,000

mol wt

15,000-30,000 by viscosity

mol wt

-

mol wt

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–2 of 2 Questions  
  1. Product P4510, Poly-ε-Cbz-L-lysine has a Cbz (carbobenzoxy) protecting group on the ε-amino group of each lysine. What are the structures of the α-amino-terminus and the carboxy-terminus, and are the end groups detectable by NMR?

    1 answer
    1. The end groups are free amino (-NH2) and carboxyl (-COOH). Because this a polydisperse material, it would be difficult to detect distinctive end groups via NMR.

      Helpful?

  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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