P4510

Poly-ε-Cbz-L-lysine

mol wt 500-4,000

• Synonym(s): N⁶-[(phenylmethoxy)carbonyl]-L-lysine homopolymer
• CAS Number: 25931-47-9
• UNSPSC Code: 12352209
• NACRES: NA.26
• MDL number: MFCD00166378

Properties

• form: powder
• Quality Segment: 200
• mol wt: 500-4,000
• color: white
• storage temp.: −20°C
• SMILES string: [N+H3][C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)[O-]
• InChI: 1S/C14H20N2O4/c15-12(13(17)18)8-4-5-9-16-14(19)20-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,15H2,(H,16,19)(H,17,18)/t12-/m0/s1
• InChI key: CKGCFBNYQJDIGS-LBPRGKRZSA-N

Description

Application

• Transfection by polyethyleneimine-coated microspheres.: This study explores the use of Poly-e-Cbz-L-lysine in coating microspheres with polyethyleneimine for enhanced cell transfection, demonstrating improved efficiency and potential applications in gene therapy (Manuel WS et al., 2001).


• Transfection of cells mediated by biodegradable polymer materials with surface-bound polyethyleneimine.: The research focuses on biodegradable polymer materials, including Poly-e-Cbz-L-lysine, for cell transfection, highlighting their biodegradability and effectiveness in delivering genetic material (Zheng J et al., 2000).


• Production of microspheres with surface amino groups from blends of Poly(Lactide-co-glycolide) and Poly(epsilon-CBZ-L-lysine) and use for encapsulation.: This paper discusses the creation of microspheres with surface amino groups using blends of Poly-e-Cbz-L-lysine, which are then used for encapsulating active agents, indicating applications in drug delivery systems (Zheng J et al., 1999).


• Modification of materials formed from poly(L-lactic acid) to enable covalent binding of biopolymers: application to high-density three-dimensional cell culture in foams with attached collagen.: The study examines the modification of poly(L-lactic acid) materials with Poly-e-Cbz-L-lysine to covalently bind biopolymers, facilitating high-density 3D cell culture applications (Zheng J et al., 1998).

Analysis Note

Molecular weight by Electrospray Mass-Spectrometry

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)