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PalGly

Name: PalGly
Brand: SIGMA

≥98% (HPLC), solid

Synonym(s):

N-(1-Oxohexadecyl)glycine, N-Hexadecanoylglycine, Hexadecanoylaminoacetic acid, N-palmitoyl glycine

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₃₅NO₃

CAS Number:

2441-41-0

Molecular Weight:

313.48

NACRES:

NA.77

PubChem Substance ID:

329820003

UNSPSC Code:

12352200

MDL number:

MFCD00153471

Assay:

≥98% (HPLC)

Form:

solid

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

solid

color

white to off-white

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

O=C(CCCCCCCCCCCCCCC)NCC(O)=O

InChI

1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)

InChI key

KVTFEOAKFFQCCX-UHFFFAOYSA-N

Description

Biochem/physiol Actions

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production.

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

Features and Benefits

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item	485756	489549	R0279
Sigma-Aldrich P0064 PalGly	Sigma-Aldrich 485756 Fmoc-Gly-OH-¹⁵N	Sigma-Aldrich 489549 Fmoc-Gly-OH-2-¹³C	Sigma-Aldrich R0279 Ro 23-9358
description ≥98% (HPLC), solid	description 98 atom % ¹⁵N	description 99 atom % ¹³C	description ≥97% (HPLC), solid
assay ≥98% (HPLC)	assay -	assay -	assay ≥97% (HPLC)
form solid	form solid	form solid	form solid
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility DMSO: >10 mg/mL	solubility -	solubility -	solubility DMSO: 16 mg/mL
color white to off-white	color -	color -	color white

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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