Very good quality for the price. Have been buying this product for years and have had no issues.
N4382
Nalidixic acid sodium salt
DNA gyrase inhibitor, powder
1 of 1 reviewers received a sample product or took part in a promotion
Synonym(s):
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|
About This Item
Empirical Formula (Hill Notation):
C12H11N2NaO3
CAS Number:
Molecular Weight:
254.22
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
222-159-7
MDL number:
Beilstein/REAXYS Number:
3580062
Form:
powder
Pricing and availability is not currently available.
Product Name
Nalidixic acid sodium salt, powder
Quality Segment
form
powder
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
DNA synthesis | interferes, enzyme | inhibits
originator
Sanofi Aventis
SMILES string
[Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12
InChI
1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1
InChI key
ROKRAUFZFDQWLE-UHFFFAOYSA-M
General description
Nalidixic acid is a quinolone and can block the activity of bacterial topoisomerase type II enzyme, thereby stopping bacterial replication. It is a potential antibacterial agent against Gram-negative bacteria than Gram-positive bacteria. Nalidixic acid has been studied in the management of urinary tract infections.
Chemical structure: quinolone
Application
Biochem/physiol Actions
Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.
Features and Benefits
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
1 of 1
This Item | ||
|---|---|---|
| description powder | description ≥98% | description analytical standard |
| form powder | form powder | form - |
| Quality Level 200 | Quality Level 200 | Quality Level 100 |
| antibiotic activity spectrum Gram-positive bacteria, Gram-negative bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - |
| mode of action enzyme | inhibits, DNA synthesis | interferes | mode of action DNA synthesis | interferes, enzyme | inhibits | mode of action - |
| originator Sanofi Aventis | originator - | originator - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.