M1809

MRS 1523

>98% (HPLC)

• Synonym(s): 3-Propyl-6-ethyl-5-[(ethylthio)carbonyl]-2 phenyl-4-propyl-3-pyridine carboxylate
• Empirical Formula (Hill Notation): C₂₃H₂₉NO₃S
• CAS Number: 212329-37-8
• Molecular Weight: 399.55
• NACRES: NA.77
• PubChem Substance ID: 24278127
• UNSPSC Code: 12352200
• MDL number: MFCD03787977
• Assay: >98% (HPLC)
• Form: oil

Properties

• Quality Segment: 100
• assay: >98% (HPLC)
• form: oil
• color: colorless to light brown
• solubility: DMSO: >10 mg/mL, H₂O: insoluble
• shipped in: wet ice
• storage temp.: 2-8°C
• SMILES string: CCCOC(=O)c1c(CCC)c(C(=O)SCC)c(CC)nc1-c2ccccc2
• InChI: 1S/C23H29NO3S/c1-5-12-17-19(23(26)28-8-4)18(7-3)24-21(16-13-10-9-11-14-16)20(17)22(25)27-15-6-2/h9-11,13-14H,5-8,12,15H2,1-4H3
• InChI key: UUSHFEVEROROSP-UHFFFAOYSA-N
• Gene Information: human ... ADORA3(140) ; rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

Description

Application

MRS 1523 has been used as an inhibitor of adenosine receptors in SW1990 and BxPC3 pancreatic cancer cells, LX2 human hepatic stellate cells and human coronary smooth muscle cells.

Biochem/physiol Actions

MRS 1523 is a selective adenosine A3 receptor antagonist in the rat.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Sold under license from the National Institutes of Health

Safety Information

• Storage Class: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves