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Merck

I7401

Anti-Interleukin-2 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-IL-2

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About This Item

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, Neutral, WB
Citations:
4
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biological source

goat

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunocytochemistry: suitable, neutralization: suitable, western blot: suitable

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL2(3558)

General description

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. It also has a vital role in modulating the expression of the IL-2 receptor and can facilitate B cell growth and differentiation. Anti-Interleukin-2 antibody can be used for neutralizing the bioactivity of recombinant human IL-2 as well as natural human IL-2. It can also be used in immunohistochemistry. Goat anti-Interleukin-2 antibody reacts specifically with recombinant human IL-2. The antibody exhibits less than 10% cross-reactivity with rmIL-2 and rrIL-2.

Immunogen

recombinant human IL-2.

Application

Anti-Interleukin-2 antibody can be used in western blotting and indirect ELISA for detecting recombinant human IL-2.

Biochem/physiol Actions

The antibody will neutralize the biological activity of recombinant and natural human IL-2. The antibody shows <10% cross reactivity with recombinant mouse and rat IL-2.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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