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L-Homoserine

Name: <SC>L</SC>-Homoserine
Brand: SIGMA

Synonym(s):

(S)-2-Amino-4-hydroxybutyric acid, Hse

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About This Item

Linear Formula:

HOCH₂CH₂CH(NH₂)CO₂H

CAS Number:

672-15-1

Molecular Weight:

119.12

NACRES:

NA.26

PubChem Substance ID:

24895748

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

211-590-6

MDL number:

MFCD00063090

Beilstein/REAXYS Number:

1721681

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Properties

assay

≥98% (TLC)

Quality Segment

100

form

powder

color

white to off-white

mp

203 °C (dec.) (lit.)

application(s)

cell analysis
detection

SMILES string

N[C@@H](CCO)C(O)=O

InChI

1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1

InChI key

UKAUYVFTDYCKQA-VKHMYHEASA-N

Description

General description

L-Homoserine is a variant of serine with an additional carbon on its side chain.

Application

L-Homoserine has been used as an internal standard for neurotransmitter analysis and amino acids quantification.

Biochem/physiol Actions

L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine.

L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.

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This Item	69453	O9014	T8441
Sigma-Aldrich H6515 L-Homoserine	Sigma-Aldrich 69453 L-Homocysteine	Sigma-Aldrich O9014 N-(3-Oxodecanoyl)-L-homoserine lactone	Sigma-Aldrich T8441 L-Threonine
description -	description ≥98.0% (NT)	description -	description from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%
form powder	form powder	form powder	form powder
assay ≥98% (TLC)	assay ≥98.0% (NT)	assay ≥98% (TLC)	assay 99.0-101.0%
mp 203 °C (dec.) (lit.)	mp 263-265 °C	mp -	mp 256 °C (dec.) (lit.)
color white to off-white	color white	color white	color white
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 300
application(s) cell analysis detection	application(s) cell analysis	application(s) cell analysis	application(s) pharmaceutical (small molecule)

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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