The Doxorubicin HCl used to prepare this product has a molecular formula of C27H29NO11 · HCl. See product D1515 at the link below for additional details:
https://www.sigmaaldrich.com/product/sigma/d1515
D5220
Doxorubicin Ready-Made
2mg/ml, Suitable for cell culture
Synonym(s):
Adriamycin, DOX, Hydroxydaunorubicin hydrochloride
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.76
Pricing and availability is not currently available.
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Quality Level
form
liquid
mol wt
579.98 Da
packaging
pkg of 1 mL
concentration
2 mg/mL
shipped in
dry ice
storage temp.
-10 to -25°C
Biochem/physiol Actions
Doxorubicin is an antitumor antibiotic that acts by inhibiting DNA topoisomerase II. It intercalates with DNA and induces apoptosis by blocking replication.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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What is the molecular formula of the doxorubicin HCl used in this solution?
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la solution de "doxorubicin ready-made" (ref D5220) est diluée dans un buffer: quelle est sa composition ? (sels de phosphates ? ou autre)
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This readymade solution contains doxorubicin hydrochloride at a concentration of 2 mg/mL in DMSO. Further information is available under "More Documents" or at this link: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/281/732/d5220pis-rev0922-ms.pdf.
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When this substance is diluted and stored at -10°C to -25°C, what is the recommended storage duration?
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This product is stable for at least 2 years in the undiluted state. Stability studies have not been performed on the material when diluted in aqueous solutions. Please see the link below to review a publication that may be helpful.
https://pubmed.ncbi.nlm.nih.gov/517541/Helpful?
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What this product is dissolved in? Is it dissolved in water ?
1 answer-
This Ready-Made solution contains doxorubicin hydrochloride at a concentration of 2 mg/mL in DMSO. This solution may be diluted further with buffer or medium.
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