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Merck

D2779

Dimethyldioctadecylammonium bromide

≥98% (TLC)

Synonym(s):

Distearyldimethylammonium bromide

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About This Item

Linear Formula:
[CH3(CH2)17]2N(Br)(CH3)2
CAS Number:
Molecular Weight:
630.95
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
EC Number:
223-037-6
Beilstein/REAXYS Number:
3580323
MDL number:
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description

cationic

Quality Level

assay

≥98% (TLC)

form

powder

mol wt

630.95 g/mol

mp

~160 °C

application(s)

cell analysis

SMILES string

CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]

InChI

1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1

InChI key

PSLWZOIUBRXAQW-UHFFFAOYSA-M

General description

Dimethyldioctadecylammonium bromide is a cationic lipid that stimulates immune responses, activates macrophages, and binds to antigens.

Application

Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV).


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Related Content


Julia F Ridpath et al.
Veterinary research communications, 34(8), 691-702 (2010-09-28)
Bovine viral diarrhea virus (BVDV) infections cause respiratory, reproductive, and enteric disease in cattle. Vaccination raises herd resistance and limits the spread of BVDV among cattle. Both killed and modified live vaccines against BVDV are available. While modified live vaccines
F S Baechtel et al.
Cancer research, 42(12), 4959-4963 (1982-12-01)
Dimethyldioctadecylammonium bromide (DDA) stimulates immune responses, primes (or activates) macrophages, and binds to antigens. Because relatively little is known about the binding of adjuvants to antigens, the nature of the interaction of DDA with soluble protein and cellular antigens was
Eloi Feitosa et al.
PloS one, 7(9), e44702-e44702 (2012-09-13)
Dioctadecyldimethylammonium bromide (DODAB) is a double chain cationic lipid, which assembles as bilayer structures in aqueous solution. The precise structures formed depend on, e.g., lipid concentration and temperature. We here combine differential scanning calorimetry (DSC) and X-ray scattering (SAXS and



Global Trade Item Number

SKUGTIN
D2779-50G04061833562543
D2779-10G04061833562536