A6751

N-Acetyl-L-tyrosine ethyl ester monohydrate

≥98%, suitable for ligand binding assays

• Synonym(s): ATEE
• Empirical Formula (Hill Notation): C₁₃H₁₇NO₄ · H₂O
• CAS Number: 36546-50-6
• Molecular Weight: 269.29
• PubChem Substance ID: 24891134
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• NACRES: NA.26
• EC Number: 212-663-5
• MDL number: MFCD00002389
• Beilstein/REAXYS Number: 2217900

Properties

• Product Name: N-Acetyl-L-tyrosine ethyl ester monohydrate,
• assay: ≥98%
• Quality Segment: 200
• form: powder
• technique(s): ligand binding assay: suitable
• color: white
• storage temp.: −20°C
• SMILES string: CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O
• InChI: 1S/C13H17NO4/c1-3-18-13(17)12(14-9(2)15)8-10-4-6-11(16)7-5-10/h4-7,12,16H,3,8H2,1-2H3,(H,14,15)/t12-/m0/s1
• InChI key: SKAWDTAMLOJQNK-LBPRGKRZSA-N

Description

General description

Substrate for chymotrypsin

Application

N-Acetyl-L-tyrosine ethyl ester monohydrate has been used:

• as a substrate in transesterification reactions with 1 M propan-1-ol catalyzed by Carlsberg protease protein-coated microcrystals (PCMC)
• to test the performance of subtilisin Carlsberg protein-coated microcrystals (PCMC)
• as a substrate for cross-linked crystals (CLECs) of subtilisin activity screening

Biochem/physiol Actions

N-Acetyl-L-tyrosine ethyl ester is an N-terminal and C-terminal protected L-tyrosine that is used in crosslinking studies and as a substrate for the detection, differentiation and/or characterization various proteases and esterases.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)