50020

β-Glycerol phosphate disodium salt pentahydrate

≥98.0% (NT)

• Synonym(s): β-GP, β-glycerolphosphate, Disodium β-glycerol phosphate pentahydrate, glycerol-2-phosphate
• Empirical Formula (Hill Notation): C₃H₇Na₂O₆P · 5H₂O
• CAS Number: 13408-09-8
• Molecular Weight: 306.11
• UNSPSC Code: 41141710
• NACRES: NA.25
• PubChem Substance ID: 57651212
• EC Number: 212-464-3
• Beilstein/REAXYS Number: 3744328
• MDL number: MFCD00149083

Properties

• Quality Segment: 200
• assay: ≥98.0% (NT)
• form: solid
• impurities: ≤2% L-α-glycerol phosphate
• loss: 26-32% loss on drying
• solubility: H₂O: 0.1 g/mL, clear, colorless
• storage temp.: 2-8°C
• SMILES string: O.O.O.O.O.[Na+].[Na+].OCC(CO)OP([O-])([O-])=O
• InChI: 1S/C3H9O6P.2Na.5H2O/c4-1-3(2-5)9-10(6,7)8;;;;;;;/h3-5H,1-2H2,(H2,6,7,8);;;5*1H2/q;2*+1;;;;;/p-2
• InChI key: PEMUISUYOHQFQH-UHFFFAOYSA-L

Description

Application

β-Glycerolphosphate (Glycerol-2-Phosphate) is used in the development of hydrogels and scaffolds that have applications in tissue engineering and cell growth and differentiation.

Biochem/physiol Actions

Beta-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression

Other Notes

Substrate for myo-inositol-1-phosphatase from bovine brain

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)