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313M-1

Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
AE1 & AE3, monoclonal
Application:
IHC (p)
Citations:
4
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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

AE1 & AE3, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (313M-14), vial of 0.5 mL concentrate (313M-15), bottle of 1.0 mL predilute (313M-17), vial of 1.0 mL concentrate (313M-16), bottle of 7.0 mL predilute (313M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

breast, colon, prostate, skin

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... KRT1(3848)

General description

Anti-cytokeratin cocktail (AE1 & AE3) is a broad-spectrum keratin antibody cocktail. It is composed of mouse monoclonal antibody AE1 that recognizes acidic type I keratins and AE3 that reacts with basic type II keratins. Both clones were generated using epidermal keratin as immunogen. This antibody is useful for identifying cells of epithelial origin and detects most carcinomas of different primarysites. This antibody cocktail can cross-react with other intermediate filaments, such as glialfibrillary acidic protein, giving false-positive staining in glial tumors.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

Cytokeratin Cocktail Positive Control Slides, Product No. 313S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
MAB3412334M-8818M-9
species reactivity

human

species reactivity

chicken, mouse, monkey, human, rabbit, bovine, rat

species reactivity

human

species reactivity

human

antibody form

culture supernatant

antibody form

purified antibody

antibody form

culture supernatant

antibody form

diluted ascites fluid

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

clone

AE1 & AE3, monoclonal

clone

AE1/AE3, monoclonal

clone

34betaE12, monoclonal

clone

B22.1 & B23.1, monoclonal

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

unconjugated

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C


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Questions

  1. Is there a broad spectrum CK cocktail that is an equivalent to the Dako MNF116?

    1 answer
    1. The closest to MNF6 (detects CK 5, 6, 8, 17, and possibly 19) is CK cocktail AE1/AE3, which detects all but CK17. Oscar detects CK 7, 8, 18, and 19.

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