89803

Methoxyamine hydrochloride

derivatization grade (GC derivatization), LiChropur^™, 97.5-102.5% (AT)

• Synonym(s): O-Methylhydroxylamine hydrochloride, Methoxylamine hydrochloride
• Linear Formula: CH₃ONH₂ · HCl
• CAS Number: 593-56-6
• Molecular Weight: 83.52
• NACRES: NA.05
• UNSPSC Code: 41116105
• Beilstein/REAXYS Number: 3589723
• MDL number: MFCD00012951
• Assay: 97.5-102.5% (AT)
• Form: crystals

Properties

• grade: derivatization grade (GC derivatization)
• Quality Segment: 100
• assay: 97.5-102.5% (AT)
• form: crystals
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Acylations
• technique(s): HPLC: suitable, LC/MS: suitable, gas chromatography (GC): suitable, ion chromatography: suitable
• mp: 151-154 °C (lit.)
• SMILES string: Cl.CON
• InChI: 1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H
• InChI key: XNXVOSBNFZWHBV-UHFFFAOYSA-N

Description

General description

Methoxyamine hydrochloride is a commonly used reagent for the generation of oxime derivatives of aldehyde- or ketone-group containing compounds. It is typically employed as an oximation reagent prior to silylation derivatizations.

Application

Methoxyamine hydrochloride can be used as:

• A reagent for the preparation of O-methyl oximes.
• A reagent used to make O-methyl oximes from aldehydes or ketones.
• An alkylation reagent.
• It may be used as a derivatization agent to improve the sensitivity of opioids, steroids and ionic metabolites in biological samples and non-volatile flavor compounds in "Angeleno" plum fruit prior to the determination of analytes using gas chromatography-mass spectrometry (GC-MS) technique.

Other Notes

Discover LiChropur^™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08,GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Codes: H290,H302 + H312,H315,H317,H319,H351,H372,H410
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable