64306

S-Methyl methanethiosulfonate

purum, ≥98.0% (GC)

• Synonym(s): S-Methyl thiomethanesulfonate, MMTS
• Linear Formula: CH₃SO₂SCH₃
• CAS Number: 2949-92-0
• Molecular Weight: 126.20
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 329759952
• EC Number: 220-970-0
• Beilstein/REAXYS Number: 1446059
• MDL number: MFCD00007565
• Assay: ≥98.0% (GC)

Properties

• grade: purum
• Quality Segment: 200
• assay: ≥98.0% (GC)
• refractive index: n20/D 1.513
• bp: 69-71 °C/0.4 mmHg (lit.)
• solubility: chloroform: 750mg + 5 ml Chloroform mg/mL, colorless to light greenish-yellow
• density: 1.337 g/mL at 20 °C, 1.337 g/mL at 25 °C (lit.)
• functional group: disulfide
• storage temp.: 2-8°C
• SMILES string: CSS(C)(=O)=O
• InChI: 1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3
• InChI key: XYONNSVDNIRXKZ-UHFFFAOYSA-N

Description

Application

• Modification of Thiol Enzymes: S-methyl methanethiosulfonate (MMTS) offers a unique method for the modification of thiol enzymes and redox-regulated proteins, providing potential applications in biochemical research focused on enzyme regulation and redox biology (Makarov et al., 2019).


• Sensor Development for Protease Activity: S-methyl methanethiosulfonate is used as a blocking reagent on the structural transitions of papain-like cysteine proteases, which supports its utility in sensor development, allowing for the detection and analysis of protease activity in various biological processes (Markovic et al., 2023).


• Agricultural Pathogen Control: Research evaluating S-methyl methanethiosulfonate as a late blight inhibitor highlights its potential as a broad-range toxin against plant pathogens, suggesting applications in agriculture for the management of crop diseases (Joller et al., 2020).

Other Notes

Methylsulfenylating agent with many applications; For the α-methylsulfenylation of cyclic ketones; Methyl disulfides from thiols; selective, reversible inactivation of enzymes

Disclaimer

may discolor to yellow on storage

Safety Information

• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H317
• pcodes: P261 - P264 - P272 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Skin Sens. 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3