40263

N,N-Dimethylformamide di-tert-butyl acetal

technical, ≥90% (GC)

• Synonym(s): 1,1-Di-tert-butoxy-N,N-dimethylmethylamine, 1,1-Di-tert-butoxytrimethylamine
• Linear Formula: (CH₃)₂NCH[OC(CH₃)₃]₂
• CAS Number: 36805-97-7
• Molecular Weight: 203.32
• Beilstein: 969629
• EC Number: 253-222-7
• MDL number: MFCD00015002
• UNSPSC Code: 12352100
• PubChem Substance ID: 329755963
• NACRES: NA.22

Properties

• grade: technical
• Quality Level: 100
• Assay: ≥90% (GC)
• form: liquid
• refractive index: n20/D 1.413 (lit.)
• bp: 56-57 °C/8 mmHg (lit.)
• density: 0.848 g/mL at 25 °C (lit.)
• SMILES string: CN(C)C(OC(C)(C)C)OC(C)(C)C
• InChI: 1S/C11H25NO2/c1-10(2,3)13-9(12(7)8)14-11(4,5)6/h9H,1-8H3
• InChI key: DBNQIOANXZVWIP-UHFFFAOYSA-N

Description

Application

N,N-Dimethylformamide di-tert-butyl acetal may be used in the synthesis of following:

• (S)-2-(1-tert-butoxycarbonyl-2-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}ethylamino)benzoic acid methyl ester
• 3-O-tert-butylmorphine
• tert-butylesters of pyrrole- and indolecarboxylic acids

Other Notes

Review; synthesis of tert-butyl esters.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H335
• Precautionary Statements: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 95.0 °F - closed cup
• Flash Point(C): 35 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves