33818

5-Hydroxythiabendazole

PESTANAL^®, analytical standard

• Synonym(s): 2-(4-Thiazolyl)-5-benzimidazolol, 5-Hydroxy-2-(4-thiazolyl)benzimidazole
• Empirical Formula (Hill Notation): C₁₀H₇N₃OS
• CAS Number: 948-71-0
• Molecular Weight: 217.25
• MDL number: MFCD00152219
• UNSPSC Code: 41116107
• PubChem Substance ID: 329754660
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: PESTANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): agriculture; environmental; forensics and toxicology; veterinary
• format: neat
• SMILES string: Oc1ccc2[nH]c(nc2c1)-c3cscn3
• InChI: 1S/C10H7N3OS/c14-6-1-2-7-8(3-6)13-10(12-7)9-4-15-5-11-9/h1-5,14H,(H,12,13)
• InChI key: VNENJHUOPQAPAT-UHFFFAOYSA-N

Description

General description

5-Hydroxythiabendazole present in excreta, eggs, edible tissues and milk is found to be the major metabolite of thiabendazole, an active ingredient in fungicidal preparations effective for plants. It can also be used as an anthelmintic drug, which is applicable both for humans and animals.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Thiabendazole and its metabolite 5-hydroxythiabendazole can undergo specific binding with monoclonal antibodies and can further undergo immobilization on agarose gels, which can find applications in immunoaffinity chromatography.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H400
• Precautionary Statements: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves