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8.55131

Dawson Dbz AM resin (100-200 mesh)

3-(Fmoc-amino)-4-aminobenzoyl AM resin (100-200 mesh) Novabiochem®

Synonym(s):

3-(Fmoc-amino)-4-aminobenzoyl Rink Amide AM resin (100 - 200 mesh), Dawson Nbz AM resin (100-200 mesh)

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About This Item

NACRES:
NA.22
UNSPSC Code:
13111023
Pricing and availability is not currently available.
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Quality Segment

200

product line

Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

A novel safety-catch resin for preparation peptide thioesters by Fmoc SPPS. Linker is activated to cleavage by thiols by treatment with CDI.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Analysis Note

Color (visual): light yellow to yellow to brown
Appearance of substance (visual): beads
Loading (photometric determination of the Fmoc-chromophore liberated upon treatment with piperidine/DMF.): 0.40 - 0.80 mmol/g
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH2Cl2): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.2 ml/g
100 - 200 mesh

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
8.550458.551198.55130
Dawson Dbz AM resin (100-200 mesh) 3-(Fmoc-amino)-4-aminobenzoyl AM resin (100-200 mesh) Novabiochem®

Sigma-Aldrich

8.55131

Dawson Dbz AM resin (100-200 mesh)

Rink Amide MBHA resin LL (100-200 mesh) Novabiochem®

Sigma-Aldrich

8.55045

Rink Amide MBHA resin LL (100-200 mesh)

Rink Amide resin HL (100-200 mesh) Novabiochem®

Sigma-Aldrich

8.55119

Rink Amide resin HL (100-200 mesh)

Rink Amide AM resin (100-200 mesh) Novabiochem®

Sigma-Aldrich

8.55130

Rink Amide AM resin (100-200 mesh)

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

functional group

amine

functional group

amine

functional group

amine

functional group

amine

Quality Level

200

Quality Level

400

Quality Level

400

Quality Level

400

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

form

beads

form

beads

form

beads

form

powder

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Questions

  1. Hi. I need a resin for my synthesis where I can deprotect both Fmoc and Boc without cleaving the peptide from the resin. Is this resin suitable for this application? or do you have any suitable safety catch resin? Many thanks.

    1 answer

    1. Unfortunately, this material is not tested for suitability for any specific application. However, a brief search of the literature suggests that it may not be compatible for Boc peptides. Please see the links below to review Fmoc and Boc resin cleavage and protection information and products that may be helpful.

      Fmoc Resin Cleavage and Deprotection:
      https://www.sigmaaldrich.com/technical-documents/technical-article/chemistry-and-synthesis/peptide-synthesis/fmoc-cleavage-deprotection

      Boc Resin Cleavage and Deprotection
      https://www.sigmaaldrich.com/technical-documents/technical-article/chemistry-and-synthesis/peptide-synthesis/boc-resin-cleavage

      Please see the link below to review an additional publication that may be helpful:
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11012524/

      Helpful?

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