8.07063

Propionyl chloride

for synthesis

• Synonym(s): Propionyl chloride, Propionic acid chloride
• Empirical Formula (Hill Notation): C₃H₅ClO
• CAS Number: 79-03-8
• Molecular Weight: 92.52
• UNSPSC Code: 12352106
• EC Index Number: 201-170-0
• NACRES: NA.22
• MDL number: MFCD00000745
• Assay: ≥98.0% (GC)
• Form: liquid

Properties

• vapor pressure: 106 hPa ( 20 °C)
• Quality Segment: 200
• assay: ≥98.0% (GC)
• form: liquid
• autoignition temp.: 270 °C
• potency: 823 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 3.6-11.9 % (v/v)
• bp: 80 °C/1013 hPa
• mp: -94 °C
• transition temp: flash point 6.5 °C
• density: 1.06 g/cm³ at 20 °C
• storage temp.: 2-30°C
• SMILES string: ClC(=O)CC
• InChI: 1S/C3H5ClO/c1-2-3(4)5/h2H2,1H3
• InChI key: RZWZRACFZGVKFM-UHFFFAOYSA-N

Description

Application

• Propionyl Chloride in Anticancer Research: Propionyl chloride is used in the synthesis of novel quinazolinone acetamides evaluated for their anticancer properties (Hakim et al., 2022).
• Propionyl Chloride in Antibacterial Agents: Used in the synthesis of nonphenolic diarylheptanoids to study their antibacterial activities (Demir et al., 2020).

Analysis Note

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.057 - 1.059
Identity (IR): passes test

Safety Information

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• hcodes: H225,H302,H314,H331
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• supp_hazards: EUH014
• Storage Class: 3 - Flammable liquids
• wgk: WGK 1
• flash_point_f: 42.8 °F - closed cup
• flash_point_c: 6 °C - closed cup