234403

Complement C3-Depleted Serum, Human

• Synonym(s): Complement serum, Human serum
• NACRES: NA.25
• UNSPSC Code: 12352202
• Form: liquid
• Shipped in: dry ice

Properties

• form: liquid
• Quality Segment: 100
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, avoid repeated freeze/thaw cycles
• color: clear yellow
• shipped in: dry ice
• storage temp.: −70°C

Description

General description

Complement C3-depleted serum is a human serum that is depleted of complement component C3. It is prepared from serum that has been shown by certified tests to be negative for Hepatitis B surface antigen (HBsAg) and antibodies to hepatitis C virus (HCV), human immunodeficiency virus (HIV-I), and HIV-II.

Application

Complement C3-Depleted Serum, Human has been used to study its effects on the α-secretase activity of umbilical cord blood serum (CBS).

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 150 mM NaCl, 50 mM sodium phosphate, pH 7.2.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HCV, HIV-I, and HIV-II.

Other Notes

Classical Pathway Activity: One C3H50 unit measured by classical pathway activation is defined as the amount of C3 required to yield 50% lysis of 3 x 10⁷ EA when incubated in the presence of the recommended volume of C3-Dpl for 30 min at 37°C in a total reaction volume of 500 µl GVB++.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable