75666
5-(Benzylthio)-1H-tetrazole
≥99.0% (HPLC)
Synonym(s):
5-Benzylmercapto-1,2,3,4-tetrazole, 5-Benzylmercaptotetrazole, 5-Benzylthio-1H-tetrazole, 5-[(Phenylmethyl)thio]-2H-tetrazole
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About This Item
Empirical Formula (Hill Notation):
C8H8N4S
CAS Number:
Molecular Weight:
192.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥99.0% (HPLC)
Form:
crystals
Pricing and availability is not currently available.
Quality Segment
assay
≥99.0% (HPLC)
form
crystals
mp
135-138 °C (DSC-onset)
functional group
phenyl, thioether
SMILES string
C(Sc1nnn[nH]1)c2ccccc2
InChI
1S/C8H8N4S/c1-2-4-7(5-3-1)6-13-8-9-11-12-10-8/h1-5H,6H2,(H,9,10,11,12)
InChI key
GXGKKIPUFAHZIZ-UHFFFAOYSA-N
General description
5-(Benzylthio)-1H-tetrazole (BTT activator) is an organic compound that is used as an activator in the synthesis of oligonucleotides. The activator reacts with the phosphoramidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′-hydroxyl group of the growing oligonucleotide chain.
Other Notes
Activator for DNA synthesis; superior alternative to tetrazole
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥99.0% (HPLC) | assay 95% | assay - | assay 99.0% |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form crystals | form - | form - | form - |
| mp 135-138 °C (DSC-onset) | mp 84-90 °C (lit.) | mp - | mp 168-175 °C (lit.) |
| functional group phenyl | functional group thioether | functional group - | functional group nitrile |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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