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110175

Sigma-Aldrich

Tetraethylene glycol

99%

Synonym(s):

Bis[2-(2-hydroxyethoxy)ethyl] ether, Tetra(ethylene glycol), Tetraglycol

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About This Item

Linear Formula:
HO(CH2CH2O)3CH2CH2OH
CAS Number:
112-60-7
Molecular Weight:
194.23
Beilstein:
1634320
EC Number:
203-989-9
MDL number:
MFCD00002879
UNSPSC Code:
12162002
eCl@ss:
39020714
PubChem Substance ID:
24846965
NACRES:
NA.23
Pricing and availability is not currently available.

vapor density

6.7 (vs air)

Quality Level

200

vapor pressure

<0.01 mmHg

Assay

99%

mol wt

average Mn 200

refractive index

n20/D 1.459 (lit.)

bp

314 °C (lit.)

mp

−5.6 °C (lit.)

density

1.125 g/mL at 25 °C (lit.)

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

OCCOCCOCCOCCO

InChI

1S/C8H18O5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h9-10H,1-8H2

InChI key

UWHCKJMYHZGTIT-UHFFFAOYSA-N

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General description

An oligomer of polyethylene glycol, tetra (ethylene glycol) (TEG) is a transparent, colorless, odorless, low volatility, hygroscopic liquid soluble in ethyl alcohol and very soluble in water.

Application

Used for the synthesis of tetraethylene glycol metha acrylate monomer.[1]

Glow discharge plasma deposition of TEG renders surfaces resistant to protein adsorption and cellular attachment.[1]

Caution

Do not confuse with glycofurol, which is also sometimes called tetraglycol.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX1922
MKCX1921
MKCW1132
MKCW4128
MKCW8477

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Rachel E Whitmire et al.
Biomaterials, 33(30), 7665-7675 (2012-07-24)
Intra-articular delivery of therapeutics to modulate osteoarthritis (OA) is challenging. Delivery of interleukin-1 receptor antagonist (IL-1Ra), the natural protein inhibitor of IL-1, to modulate IL-1-based inflammation through gene therapy or bolus protein injections has emerged as a promising therapy for
Rieko Asai et al.
Scientific reports, 7(1), 8955-8955 (2017-08-23)
The somatopleure is the amniotic primordium in amniote development, but its boundary to the embryonic body at early embryonic stages and the fate of cells constituting this structure are not well characterized. It also remains unclear how cells behave during
Andrea Paolella et al.
Nature communications, 8, 14643-14643 (2017-04-11)
Recently, intensive efforts are dedicated to convert and store the solar energy in a single device. Herein, dye-synthesized solar cell technology is combined with lithium-ion materials to investigate light-assisted battery charging. In particular we report the direct photo-oxidation of lithium
Takashi Nakamura et al.
Nanomaterials (Basel, Switzerland), 8(8) (2018-08-17)
Copper nitride particles have a low decomposition temperature, they absorb light, and are oxidation-resistant, making them potentially useful for the development of novel wiring inks for printing circuit boards by means of intense pulsed light (IPL) sintering at low-energy. Here
Nicholas M Negretti et al.
Scientific reports, 7(1), 15455-15455 (2017-11-15)
Bile plays an important role in digestion, absorption of fats, and the excretion of waste products, while concurrently providing a critical barrier against colonization by harmful bacteria. Previous studies have demonstrated that gut pathogens react to bile by adapting their
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Can it be used for dissolving drug for in vivo mice experiments?

    1 answer

    1. This product has not been tested for any specific application. However, it has been used successfully for in vivo applications by researchers. Please see the link below to review a publication that may be helpful:
      https://onlinelibrary.wiley.com/doi/10.1002/jbm.a.36212

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