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P6024

Sigma-Aldrich

Putrescine dihydrochloride

γ-irradiated, lyophilized powder, BioXtra, suitable for cell culture

Synonym(s):

1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride

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About This Item

Linear Formula:
NH2(CH2)4NH2 · 2HCl
CAS Number:
333-93-7
Molecular Weight:
161.07
Beilstein:
3906680
EC Number:
206-375-9
MDL number:
MFCD00012526
UNSPSC Code:
12352207
PubChem Substance ID:
24898727
NACRES:
NA.75

biological source

synthetic (organic)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

Assay

≥97% (HPLC)

form

lyophilized powder

technique(s)

cell culture | mammalian: suitable

mp

280 °C (dec.) (lit.)

solubility

cell culture medium: 0.16 mg/mL

storage temp.

room temp

SMILES string

Cl[H].Cl[H].NCCCCN

InChI

1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H

InChI key

XXWCODXIQWIHQN-UHFFFAOYSA-N

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Related Categories

Biochem/physiol Actions

Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H302,H311,H314,H330

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Yong Tao et al.
Human reproduction (Oxford, England), 30(8), 1867-1875 (2015-06-18)
Does peri-ovulatory putrescine supplementation of older mice improve oocyte quality and reduce the incidence of embryo resorption? Peri-ovulatory putrescine supplementation in older mice improved oocyte quality, as indicated by increased blastocyst cell numbers and reduced the incidence of embryo resorption.
Injae Hwang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(6), 2397-2411 (2015-02-26)
Firmicutes and Bacteroidetes, 2 major phyla of gut microbiota, are involved in lipid and bile acid metabolism to maintain systemic energy homeostasis in host. Recently, accumulating evidence has suggested that dietary changes promptly induce the alteration of abundance of both
Quan Findlay et al.
American journal of physiology. Gastrointestinal and liver physiology, 307(7), G741-G748 (2014-08-16)
Gut motility disorders can result from an absent, damaged, or dysfunctional enteric nervous system (ENS). Cell therapy is an exciting prospect to treat these enteric neuropathies and restore gut motility. Previous studies have examined a variety of sources of stem/progenitor
Tadeu Chaves de Figueiredo et al.
Talanta, 142, 240-245 (2015-05-25)
A quantitative and confirmatory high-performance liquid chromatography with ultraviolet detection (HPLC-UV) method for the determination of bioactive amines in the albumen and yolk of commercial eggs was developed, optimized and validated by analyte extraction with trichloroacetic acid and pre-column derivatization
Suk Ho Bhang et al.
Biomaterials, 55, 33-43 (2015-05-03)
At high concentrations, manganese (Mn) promotes cellular neurodevelopment but causes toxicity. Here, we report that Mn ion at high concentrations can be delivered to pheochromocytoma 12 (PC12) cells using gold nanoparticles (AuNPs) to enhance cellular neurodevelopment without toxicity. Mn(2+) release
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