G1029

Monoclonal Anti-Granulocyte Colony Stimulating Factor antibody produced in mouse

clone 3316.111, purified immunoglobulin, lyophilized powder

• Synonym(s): Anti-G-CSF
• MDL number: MFCD00162357
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 3316.111, monoclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): capture ELISA: suitable; neutralization: suitable
• isotype: IgG1
• UniProt accession no.: P09919
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CSF3(1440)

Description

Immunogen

recombinant human granulocyte colony stimulating factor.

Biochem/physiol Actions

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable