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Key Documents

C1426

Sigma-Aldrich

Cesium methanesulfonate

used in patch clamp techniques

Synonym(s):

CsMSF, CsMeS, Methanesulfonic acid cesium salt

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About This Item

Linear Formula:
CH3O3SCs
CAS Number:
Molecular Weight:
228.00
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25
grade:
for analytical purposes
form:
powder

grade

for analytical purposes

form

powder

mp

262-264 °C (lit.)

SMILES string

[Cs+].CS([O-])(=O)=O

InChI

1S/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1

InChI key

DJKJXRLREATOMF-UHFFFAOYSA-M

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General description

Cesium methanesulfonate is used as a component of intracellular recording solutions of electrodes for patch clamp techniques in cell electrophysiology studies. Cesium methanesulfonate is used as an current carrier as cesium acts as a potassium (K+) channel blocker, while methanesulfonate is not transported through chloride (Cl-) channels.

Application

Cesium methanesulfonate has been used as a supplement in intracellular solution for the patch clamp recording system.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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L Zhang et al.
Pflugers Archiv : European journal of physiology, 426(3-4), 247-253 (1994-02-01)
Using the whole-cell recording technique, we have examined the slow Ca(2+)-activated afterhyperpolarization (AHP) and its underlying current (IAHP) in hippocampal CA1 neurones of brain slices obtained from mature rats. Specifically we have studied the effects of the anion component of
D Mouginot et al.
Journal of neurophysiology, 75(2), 894-901 (1996-02-01)
1. Recording from deep cerebellar nuclei neurons, we investigated the role of presynaptic gamma-aminobutyric acid-B (GABAB) receptors in the modulation of monosynaptic inhibitory postsynaptic potentials (IPSPs) evoked by stimulation of Purkinje cells in rat slice cultures. 2. Bath application of
P L Li et al.
American journal of physiology. Heart and circulatory physiology, 280(1), H208-H215 (2000-12-21)
The present study was designed to test the hypothesis that cADP-ribose (cADPR) increases Ca(2+) release through activation of ryanodine receptors (RYR) on the sarcoplasmic reticulum (SR) in coronary arterial smooth muscle cells (CASMCs). We reconstituted RYR from the SR of
Diverse voltage-sensitive dyes modulate GABAA receptor function.
Mennerick., S., et al.
The Journal of Neuroscience, 24, 2871-2879 (2010)
An optogenetics- and imaging-assisted simultaneous multiple patch-clamp recording system for decoding complex neural circuits.
Wang G
Nature Protocols, 10, 397-397 (2015)

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