6906-50A
Human Peripheral Blood Monocytes: HPBM
Synonym(s):
HPBM, HPBM cells
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About This Item
UNSPSC Code:
41106514
NACRES:
NA.81
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biological source
human peripheral blood
form
liquid
packaging
pkg of 5,000,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Suspension
technique(s)
cell culture | mammalian: suitable
shipped in
dry ice
storage temp.
−196°C
General description
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Human Peripheral Blood Monocytes (HPBM) provide a useful in vitro tool for studying various aspects of pathology and biology. Our CD14+ Monocytes are isolated and purified from human peripheral blood of healthy donors and cryopreserved immediately after isolation.
HPBM are the precursors of tissue macrophages and dentritic cells and are central to immunological responses, including cell-mediated cytotoxicity and production of inflammatory mediators. The CD14 monocyte subset expresses a component of the lipopolysaccharide (LPS) receptor complex, are large with diameter of ~18 um, represent ~80%–90% of circulating monocytes, and express higher levels of CD62L (L-selectin) and CD11b (also referred to as Mac-1 or CR3) and lower levels of MHC class II than do CD16+ monocytes.
Human Peripheral Blood Monocytes (HPBM) provide a useful in vitro tool for studying various aspects of pathology and biology. Our CD14+ Monocytes are isolated and purified from human peripheral blood of healthy donors and cryopreserved immediately after isolation.
HPBM are the precursors of tissue macrophages and dentritic cells and are central to immunological responses, including cell-mediated cytotoxicity and production of inflammatory mediators. The CD14 monocyte subset expresses a component of the lipopolysaccharide (LPS) receptor complex, are large with diameter of ~18 um, represent ~80%–90% of circulating monocytes, and express higher levels of CD62L (L-selectin) and CD11b (also referred to as Mac-1 or CR3) and lower levels of MHC class II than do CD16+ monocytes.
Cell Line Origin
Blood
Application
Immune system dysfunction. Immunological responses, cell-mediated cytotoxicity, production of inflammatory mediators, hematopoiesis, myeloid differentiation, lipopolysaccharide (LPS), receptor complexes, CD62L (L-selectin), CD11b (Mac-1 or CR3), MHC class II.
Packaging
Immediately after isolation, 5,000,000 cells in DMEM containing 45% FBS & 10% DMSO.
Components
DMEM containing 45% FBS & 10% DMSO
Quality
Each lot was tested for proper morphology, CD14 positive selection, Negative for HIV, Hepatitis B, Hepatitis C
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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