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46842

Supelco

Sulfamethizole

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide, N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide, Sulfamethylthiadiazole

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About This Item

Empirical Formula (Hill Notation):
C9H10N4O2S2
CAS Number:
144-82-1
Molecular Weight:
270.33
Beilstein:
255002
EC Number:
205-641-1
MDL number:
MFCD00053363
UNSPSC Code:
41116107
PubChem Substance ID:
329757249
NACRES:
NA.24

grade

analytical standard

Quality Level

200

Agency

EPA 1694

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

InChI

1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)

InChI key

VACCAVUAMIDAGB-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCH4894
BCCG5802
BCBT9838
BCBR8047V
SZBD030XV

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Sigma-Aldrich

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Janez Seliger et al.
Physical chemistry chemical physics : PCCP, 12(40), 13007-13019 (2010-09-08)
The 1,3,4-thiadiazole derivatives (2-amino-1,3,4-thiadiazole, acetazolamide, sulfamethizole) have been studied experimentally in the solid state by (1)H-(14)N NQDR spectroscopy and theoretically by Density Functional Theory (DFT). The specific pattern of the intra and intermolecular interactions in 1,3,4-thiadiazole derivatives is described within
Stephen P Mezyk et al.
The journal of physical chemistry. A, 111(37), 9019-9024 (2007-08-25)
Absolute rate constants and degradation efficiencies for hydroxyl radical and hydrated electron reactions with four different sulfa drugs in water have been evaluated using a combination of electron pulse radiolysis/absorption spectroscopy and steady-state radiolysis/high-performance liquid chromatography measurements. For sulfamethazine, sulfamethizole
Robert R Muder
Seminars in respiratory and critical care medicine, 28(6), 672-677 (2007-12-21)
Stenotrophomonas (Xanthomonas) maltophilia is a nonfermentative, gram-negative bacillus that is widely distributed in natural and human-made environments. In the nonhospital setting it is an uncommon pathogen, typically causing soft tissue infection of contaminated wounds. In the hospital setting, particularly among
Ali Md Ahad et al.
Bioorganic & medicinal chemistry, 19(6), 2046-2054 (2011-03-01)
Disruption of the phosphatidylinositol 3-kinase/AKT signaling pathway can lead to apoptosis in cancer cells. Previously we identified a lead sulfonamide that selectively bound to the pleckstrin homology (PH) domain of AKT and induced apoptosis when present at low micromolar concentrations.
Tony L Yaksh et al.
Anesthesiology, 108(5), 938-949 (2008-04-24)
Intrathecal N-methyl-d-aspartate antagonists have antihyperalgesic efficacy. The authors examined toxicity in a canine model of chronic lumbar intrathecal infusion. Dogs (10-16 kg) were prepared with lumbar intrathecal catheters connected to vest-mounted pumps (100 microl/h). In phase 1, stepwise incrementations in
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