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Key Documents

46453

Supelco

6-Methyl-2-thiouracil

VETRANAL®, analytical standard

Synonym(s):

4-Hydroxy-2-mercapto 6-methylpyrimidine, MZU

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About This Item

Empirical Formula (Hill Notation):
C5H6N2OS
CAS Number:
Molecular Weight:
142.18
Beilstein:
115648
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

~330 °C (dec.) (lit.)

application(s)

clinical testing

format

neat

SMILES string

CC1=CC(=O)NC(=S)N1

InChI

1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

InChI key

HWGBHCRJGXAGEU-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Joseph F Contrera et al.
Regulatory toxicology and pharmacology : RTP, 38(3), 243-259 (2003-11-19)
MDL QSAR (formerly SciVision QSAR IS) software is one of the several software systems under evaluation by the Informatics and Computational Safety Analysis Staff (ICSAS) of the FDA Center for Drug Evaluation and Research for regulatory and scientific decision support
F R Lima et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(6), 2028-2038 (2001-03-14)
The postnatal development of rat microglia is marked by an important increase in the number of microglial cells and the growth of their ramified processes. We studied the role of thyroid hormone in microglial development. The distribution and morphology of
A Tohei et al.
The Journal of veterinary medical science, 60(4), 439-446 (1998-05-21)
The effect of hypothyroidism on adrenals and gonads in adult female rats was investigated throughout the estrous cycle. Hypothyroidism was induced by administration of 4-Methyl-2-Thiouracil (Thiouracil) in the drinking water. The weight of ovaries and adrenals, and the plasma levels
T Merkulova et al.
American journal of physiology. Endocrinology and metabolism, 278(2), E330-E339 (2000-02-09)
During muscle development, an isozymic transition of the glycolytic enzyme enolase occurs from the embryonic and ubiquitous alphaalpha-isoform to the muscle-specific betabeta-isoform. Here, we demonstrate a stimulatory role of thyroid hormones on these two enolase genes during rat development in
P Batjoens et al.
Journal of chromatography. A, 750(1-2), 127-132 (1996-10-25)
A more sensitive method was developed using the hyphenated technique of gas chromatography-mass spectrometry (GC-MS) supplementary to the official high-performance thin-layer chromatography (HPTLC) method. Even combined with less efficient extraction and clean-up methods, GC-MS is able to lower the detection

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