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24-2109

Sigma-Aldrich

3-Methyl-1-phenyl-2-pyrazoline-5-one

Synonym(s):

5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

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About This Item

Empirical Formula (Hill Notation):
C10H10N2O
CAS Number:
89-25-8
Molecular Weight:
174.20
Beilstein:
609575
EC Number:
201-891-0
MDL number:
MFCD00003138
UNSPSC Code:
12352005
PubChem Substance ID:
329752598

form

solid

availability

available only in Japan

bp

287 °C/265 mmHg (lit.)

mp

126-128 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC1=NN(C(=O)C1)c2ccccc2

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

InChI key

QELUYTUMUWHWMC-UHFFFAOYSA-N

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Suitability

environmental analysis

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ajmal Ahmad et al.
Molecular and cellular biochemistry, 367(1-2), 215-225 (2012-06-01)
Stroke is a life-threatening disease with major cause of mortality and morbidity worldwide. The neuronal damage following cerebral ischemia is a serious risk to stroke patients. Oxidative stress and apoptotic damage play an important role in cerebral ischemic pathogenesis and
Manabu Ohta et al.
Brain research, 1490, 184-192 (2012-09-18)
Traumatic axonal injury (TAI), a feature of traumatic brain injury (TBI), progressively evolves over hours through impaired axonal transport and is thought to be a major contributor to cognitive dysfunction. In spite of various studies suggesting that pharmacologic or physiologic
Laura Monturiol-Gross et al.
The Journal of infectious diseases, 206(8), 1218-1226 (2012-08-21)
Clostridium perfringens, the most broadly distributed pathogen in nature, produces a prototype phospholipase C, also called α-toxin, which plays a key role in the pathogenesis of gas gangrene. α-Toxin causes plasma membrane disruption at high concentrations, but the role of
Mitsugi Shimoda et al.
World journal of gastroenterology, 18(27), 3520-3526 (2012-07-25)
To investigate the effect of E3-methyl-1-phenyl-2-pyrazolin-5-one (Edr) on hepatic ischemia-reperfusion (I/R) injury and liver regeneration in a porcine hepatectomy model. One hour ischemia was induced by occluding the vessels and the bile duct of the right and median lobes. A
Nobukazu Miyamoto et al.
Stroke, 44(12), 3516-3521 (2013-09-28)
White matter injury caused by cerebral hypoperfusion may contribute to the pathophysiology of vascular dementia and stroke, but the underlying mechanisms remain to be fully defined. Here, we test the hypothesis that oxidative stress interferes with endogenous white matter repair
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