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M6204

Sigma-Aldrich

2-Thiazoline-2-thiol

98%

Synonym(s):

2-Mercapto-2-thiazoline

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About This Item

Empirical Formula (Hill Notation):
C3H5NS2
CAS Number:
96-53-7
Molecular Weight:
119.21
Beilstein:
106332
EC Number:
202-512-1
MDL number:
MFCD00126013
UNSPSC Code:
12352100
PubChem Substance ID:
24897083
NACRES:
NA.22

Quality Level

200

Assay

98%

mp

100-105 °C (lit.)

SMILES string

S=C1NCCS1

InChI

1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)

InChI key

WGJCBBASTRWVJL-UHFFFAOYSA-N

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Application

Tool for highly selective chiral syntheses of penam- and carbapenam-type β-lactam antibiotics.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P301 + P310

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Stud. Org. Chem., 28, 57-57 (1987)
Yahia N Mabkhot et al.
Molecules (Basel, Switzerland), 24(9) (2019-05-01)
A series of new thiazoline derivatives were synthesized. Structure analyses were accomplished employing 1H-NMR, 13C-NMR, X-ray and MS techniques. The in vitro antitumor activities were assessed against human hepatocellular carcinoma (HepG-2) and colorectal carcinoma (HCT-116) cell lines. The results revealed
Taro Hase et al.
Urology, 60(3), 542-547 (2002-09-28)
To investigate the expression of peroxisome proliferator activator-receptor (PPAR)-alpha, beta, and gamma in human testicular cancer (TC) and normal testicular (NT) tissues, as well as the effects of the PPAR-gamma ligand. Recent studies have demonstrated that PPAR-gamma is expressed in
Cestmír Konák et al.
Langmuir : the ACS journal of surfaces and colloids, 24(14), 7092-7098 (2008-06-12)
Vesicles bearing either cationic (amino) groups or zwitterionic (amino acid) groups on the surface were coated with a reactive multivalent hydrophilic N-(2-hydroxypropyl)methacrylamide polymer (PHPMA) and its positively charged analogue (3 mol % quaternary ammonium groups), both having reactive thiazolidine-2-thione (TT)
Vladimír Subr et al.
Biomacromolecules, 7(1), 122-130 (2006-01-10)
N-(2-Hydroxypropyl)methacrylamide (HPMA) copolymers (pHPMA) containing 4-nitrophenyl ester (ONp) or thiazolidine-2-thione (TT) reactive groups in side chains and telechelic/semitelechelic pHPMA with TT groups were designed as highly hydrophilic biocompatible polymers suitable for chemical coating of polyelectrolyte-based DNA-containing nanoparticles bearing amino groups
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