934798
Gelatin acrylate
gel strength 300 g Bloom, degree of substitution 60%
Synonym(s):
Gelatin acrylate, Acrylated gelatin
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About This Item
Linear Formula:
(C40H59N11O13)n
UNSPSC Code:
12352202
NACRES:
NA.21
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General description
Gelatin is a natural biopolymer derived from collagen that plays an important role in the biomedical field due to its biocompatibility, biodegradability, and nonimmunogenicity. Acrylate-functionalized gelatin, or gelatin acrylate, can be crosslinked using thiol-Michael click chemistry as well as photochemical crosslinking. It′s properties are very similar to gelatin methacrylate (GelMA). Crosslinked gelatin hydrogels have many applications in tissue engineering and 3D bioprinting.
Application
- Endothelial cell morphogenesis
- Injectable tissue constructs
- Tissue engineering of multiple tissue types including heart tissue (cardiomyocytes), bone tissue (osteogenesis), cartilage tissue (chondrogenesis), and epidermal tissue
- Drug delivery applications including contact lens and dental
Features and Benefits
- Photopolymerizable
- Clickable
- Biocompatible
- Biodegradable
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Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Hongyuan Zhu et al.
Journal of the mechanical behavior of biomedical materials, 88, 160-169 (2018-09-03)
Biocompatible hydrogels with defined mechanical properties are critical to tissue engineering and regenerative medicine. Thiol-acrylate photopolymerized hydrogels have attracted special interest for their degradability and cytocompatibility, and for their tunable mechanical properties through controlling factors that affect reaction kinetics (e.g.
Kelly M C Tsang et al.
Advanced functional materials, 25(6), 977-986 (2015-09-04)
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization in vitro. Researchers have incorporated photodegradable moieties into synthetic polymeric hydrogels as a means of achieving spatiotemporal control over material properties. In this study protein-based photodegradable hydrogels
Xin Zhao et al.
Advanced healthcare materials, 5(1), 108-118 (2015-04-17)
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels used to support epidermal regeneration are mainly collagen- or gelatin-based, which mimic the natural dermal extracellular matrix but often suffer from insufficient and uncontrollable mechanical and degradation properties. In
Chaenyung Cha et al.
Biomacromolecules, 15(1), 283-290 (2013-12-19)
Microfabrication technology provides a highly versatile platform for engineering hydrogels used in biomedical applications with high-resolution control and injectability. Herein, we present a strategy of microfluidics-assisted fabrication photo-cross-linkable gelatin microgels, coupled with providing protective silica hydrogel layer on the microgel
Thomas Billiet et al.
Biomaterials, 35(1), 49-62 (2013-10-12)
In the present study, we report on the combined efforts of material chemistry, engineering and biology as a systemic approach for the fabrication of high viability 3D printed macroporous gelatin methacrylamide constructs. First, we propose the use and optimization of
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