Skip to Content
Merck
All Photos(3)

Documents

289094

Sigma-Aldrich

tert-Butyldimethylsilanol

99%

Synonym(s):

1-(1,1-Dimethylethyl)-1,1-dimethylsilanol, tert-Butyl(hydroxy)dimethylsilane, tert-Butyldimethylsilanol, tert-Butyldimethylsilyl hydroxide, Dimethyl-tert-butylsilanol

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3)3CSi(CH3)2OH
CAS Number:
Molecular Weight:
132.28
Beilstein:
1732777
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

liquid

refractive index

n20/D 1.424 (lit.)

bp

139 °C/739 mmHg (lit.)

density

0.84 g/mL at 25 °C (lit.)

SMILES string

CC(C)(C)[Si](C)(C)O

InChI

1S/C6H16OSi/c1-6(2,3)8(4,5)7/h7H,1-5H3

InChI key

FGWRMMTYIZKYMA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

tert-Butyldimethylsilanol can be used as a silylating agent for the protection of hydroxyl groups via silylation. It is used:
  • For the preparation of α-chiral ether derivatives by catalytic asymmetric allylic substitution.
  • As an initiator for the polymerization of 1,2 benzenedicarboxaldehyde.
  • In the synthesis of enol silyl ethers.

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

113.0 °F - closed cup

Flash Point(C)

45 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Direct, Iridium-Catalyzed Enantioselective and Regioselective Allylic Etherification with Aliphatic Alcohols
Ueno S and Hartwig J
Angewandte Chemie (International ed. in English), 47(10), 1928-1931 (2008)
Enol Silyl Ethers via Copper (II)-Catalyzed C-O Bond Formation
Chan DG, et al.
Organic Letters, 13(10), 2778-2781 (2011)
Synthesis of hydrolytically stable porphyrin C-and S-glycoconjugates in high yields
Pasetto P, et al.
Chemical Communications (Cambridge, England), 81-82 (2001)
Reproducible and scalable synthesis of end-cap-functionalized depolymerizable poly (phthalaldehydes)
DiLauro AM, et al.
Macromolecules, 46(8), 2963-2968 (2013)
Wei Hong et al.
International journal of nanomedicine, 13, 6297-6309 (2018-10-24)
Multidrug-resistant (MDR) Streptococcus pneumonia constitute a major worldwide public health concern. In our preliminary study, PEGylated nano-self-assemblies of bacitracin A (PEGylated Nano-BA12K) showed strong antibacterial potency against reference S. pneumonia strain (ATCC 49619). In this study, the possibility of applying

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service