U6885
Uridine-5′-diphosphoglucose Dehydrogenase from Streptococcus pyogenes
recombinant, expressed in E. coli, Type VI, lyophilized powder
Synonym(s):
UDP-glucose:NAD+ 6-oxidoreductase
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About This Item
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Pricing and availability is not currently available.
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recombinant
expressed in E. coli
Quality Level
type
Type VI
Assay
≥95% (SDS-PAGE)
form
lyophilized powder
mol wt
~47 kDa
shipped in
dry ice
storage temp.
−70°C
Unit Definition
One unit will oxidize 1.0 μmole of UDP-glucose to UDP-glucuronic acid per minute at pH 8.7 at 25 °C.
Physical form
Lyophilized powder containing ~70% PBS and ~20% sorbitol.
Preparation Note
Animal component free
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Annastasia S Hyde et al.
The Journal of biological chemistry, 288(49), 35049-35057 (2013-10-23)
UDP-glucose dehydrogenase (UGDH) provides precursors for steroid elimination, hyaluronan production, and glycosaminoglycan synthesis. The wild-type UGDH enzyme purifies in a hexamer-dimer equilibrium and transiently undergoes dynamic motion that exposes the dimer-dimer interface during catalysis. In the current study we created
Simone Superina et al.
Developmental biology, 387(2), 154-166 (2014-01-28)
Growth factors and morphogens regulate embryonic patterning, cell fate specification, cell migration, and morphogenesis. The activity and behavior of these signaling molecules are regulated in the extracellular space through interactions with proteoglycans (Bernfield et al., 1999; Perrimon and Bernfield 2000;
Haifeng Li et al.
Applied biochemistry and biotechnology, 178(6), 1141-1153 (2015-11-29)
UDPG pyrophosphatase (UGPase) plays an important role in carbohydrate metabolism, catalyzing a reversible production of uridine diphosphate glucose (UDPG) and pyrophosphate (PPi) from Glc-1-P and UTP. UGPase gene from Aureobasidium pullulans NRRL Y-12974 was cloned, overexpressed in Escherichia coli. The
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