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RAB0857

Sigma-Aldrich

Mouse Ptx3 / Pentraxin-related Protein PTX3 ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.6 ng/mL
standard curve range: 0.614-150 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Ptx3(19288)

General description

The antibody pair provided in this kit recognizes mouse Pentraxin-related Protein PTX3 / Pentraxin 3.
The pentraxin3 (PTX3) gene encodes for a long PTX3 protein, an acute-phase protein. PTX3 protein is a member of the pentraxin family and is present in several cells and tissues. It is observed during brain inflammatory response and seizure. PTX3 plays a role in angiogenesis, tissue remodeling, and female fertility. It promotes phagocytosis of pathogen and inhibits the phagocytosis of apoptotic cells. The antibody pair provided in this kit recognizes mouse pentraxin-related protein PTX3 / pentraxin 3.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yue Liu et al.
Phytotherapy research : PTR, 33(9), 2401-2408 (2019-07-19)
Lupus nephritis (LN) is an autoimmune disease caused by systemic lupus erythematosus. Excessive proliferation of mesangial cells is one of the most serious pathological manifestations of LN. In addition, the expression of PTX3 is elevated in the serum of patients
Shinnosuke Kikuchi et al.
Heart and vessels, 34(6), 1002-1013 (2019-01-02)
Some experimental studies have shown that direct oral anticoagulants (DOACs) have anti-inflammatory effects. However, the interval changes in inflammatory markers in patients with non-valvular atrial fibrillation (AF) who receive DOACs remain unknown. Between July 2013 and April 2014, a total
Jingbo Zhang et al.
PloS one, 14(8), e0220772-e0220772 (2019-08-23)
Pentraxin-3 (PTX3) is a multifunctional protein involved in both innate and adaptive immunity. Glucocorticoid (GC) is the first-line therapy to mitigate airway inflammation in asthma. Previous pieces of evidence showed that GC has divergent effects on PTX3 production in various
L Wirestam et al.
Clinical and experimental immunology, 189(1), 83-91 (2017-03-04)
Dysfunctional elimination of cell debris, and the role of opsonins such as pentraxins, is of interest regarding systemic lupus erythematosus (SLE) pathogenesis. Interferon (IFN)-α is typically elevated during SLE flares, and inhibits hepatocyte production of the pentraxin 'C-reactive protein' (CRP)
T Zelante et al.
Mucosal immunology, 10(2), 470-480 (2016-06-16)
Treatment of post-transplant patients with immunosuppressive drugs targeting the calcineurin-nuclear factor of activated T cells (NFAT) pathway, including cyclosporine A or tacrolimus, is commonly associated with a higher incidence of opportunistic infections, such as Aspergillus fumigatus, which can lead to
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